I use infuse on MacOS, Apple TV and iOS, primarily for streaming from Plex. The difference is night and day compared to the native app.
On Apple TV, for example, Infuse is the only way to play some of the bluray media natively, as the native Plex app forces a transcode on some audio files.
My only gripe is the UI/UX.. The native Plex app is lightyears ahead of Infuse in terms of brownsing the library. This REALLY needs work, as I'd use Infuse as the primary app if it mirrored how nice Plex is in this respect. At the moment I flick between Plex and Infuse when needed, which is also a pain.